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. 2010 Jul 7;25(12):2724–2734. doi: 10.1002/jbmr.177

Table 2.

Odds Ratio of Receiving the Highest Paricalcitol Dose (≥10 µg/Week, n = 32,327) Versus the Lowest Paricalcitol Dose (>0 to <10 µg/Week, n = 17,347) in 49,674 Hemodialysis Patients Who Received Any Dose of Paricalcitol During All 20 Calendar Quarters of the Cohort (July 2001 to June 2006)

Unadjusted Case-mix adjusted
Age (each 10-year increase) 0.8 (0.7–0.8)* 0.8 (0.8–0.9)*
Gender (women versus men) 1.0 (1.0–1.1) 1.0 (1.0–1.1)
Diabetes mellitus (versus no diabetes) 0.9 (0.8–0.9)* 0.9 (0.9–1.0)*
Race/ethnicity
 Non-Hispanic whites (reference) 1 1
 African Americans 2.6 (2.5–2.7)* 2.1 (2.0–2.2)*
 Hispanics 1.1 (1.0–1.1)* 0.9 (0.8–1.0)*
 Asians 0.7 (0.7–0.8)* 0.6 (0.6–0.7)*
Dialysis treatment vintage time
  < 6 Months (reference) 1 1
 6–24 Months 1.1 (1.1–1.2)* 1.0 (1.0–1.1)
 2–5 Years 1.7 (1.6–1.8)* 1.5 (1.4–1.6)*
  > 5 Years 2.6 (2.4–2.7)* 2.1 (1.9–2.3)*
Primary insurance
 Medicare (reference) 1 1
 Medicaid 1.3 (1.1–1.4)* 0.9 (0.9–1.0)*
 Private insurance 1.1 (1.0–1.1) 0.9 (0.9–1.1)
Kt/V (each 0.1-unit increase) 1.0 (0.9–1.0)* 1.0 (0.9–1.0)*
nPCR (nPNA) (each 0.1 g/kg/day increase) 1.0 (1.0–1.1)* 1.0 (1.0–1.1)*
BMI (each 1 kg/m2 increase) 1.0 (1.0–1.1)* 1.0 (1.0–1.1)*
Biochemical measures
 Albumin (each 0.1 g/dL increase) 1.1 (1.0–1.1)* 1.0 (1.0–1.1)*
 Creatinine (each 1 mg/dL increase) 1.2 (1.1–1.2)* 1.1 (1.0–1.1)*
 TIBC (each 10 mg/dL increase) 1.0 (1.0–1.1)* 1.0 (1.0–1.1)*
 Phosphorus (each 1 mg/dL increase) 1.4 (1.3–1.4)* 1.3 (1.3–1.4)*
 Calciuma (each 1 mg/dL increase) 1.4 (1.3–1.4)* 1.4 (1.3–1.4)*
 Ferritin (each 100 ng/mL increase) 1.0 (1.0–1.1)* 1.0 (0.9–1.0)
 Hemoglobin (each 1 g/dL increase) 1.0 (0.9–1.0)* 1.0 (0.9–1.0)*
 WBC (each 103/µL increase) 0.9 (0.9–1.0)* 1.0 (0.9–1.0)*
 Lymphocyte (each 1% of total WBC increase) 1.0 (1.0–1.1)* 1.0 (1.0–1.1)*
 Intact PTH (each 100 pg/mL increase) 1.4 (1.3–1.4)* 1.3 (1.3–1.4)*
 Alkaline phosphatase (each 10 U/L increase) 1.0 (1.0–1.1)* 1.1 (1.0–1.1)*

nPCR, normalized protein catabolic rate; nPNA, normalized protein nitrogen appearance.

a

Serum calcium is adjusted for serum albumin.

*

p < .001.