Fig. 2.

Sequencing results of FKBP10 mutations (cases 1 through 4). Patient pedigrees are aligned above patient chromatograms, demonstrating their respective mutation in FKBP10. Below the patient chromatogram is a control chromatogram aligned to depict wild-type DNA sequence at the position of patient mutations. Cases 1 and 2 and siblings, cases 3 and 4, are depicted. Red boxes represent nucleotide base pair insertions. Dashed red lines represent junctional sites, where a deletion has occurred (red arrows indicate direction of junctioning). Asterisks (^*) depict patients with DNA available for sequencing. The mutation for each patient is listed beneath his or her respective chromatogram.