Table 2.
Nuclear Factors Identified by Mass Spectroscopy at the Osx TNF-α Element With Known Differentiation Regulatory, Transcriptional Regulatory, or TNF-α-Responsive Functions
| Factor | Known functions | Accession number |
|---|---|---|
| TNF-induced | ||
| TIF1β Tripartite motif protein 28 | Transcriptional coactivator of nuclear receptors | Q62318 |
| HSC71 Heat shock cognate 71-kDa protein | TNF-induced chaperone protein | P63017 |
| Radixin (ESP-10) | Component of “merlin” complex; regulation of NF-κB-induced transcription, actin-modifying protein | P26043 |
| Ewing sarcoma homologue | Associates with TFIID | Q5SUS9 |
| PRX1 Paired mesoderm homeobox protein 1 | Early limb bud, bone, and vascular differentiation factor | P63013 |
| TNF-displaced | ||
| CRP-2 Cysteine-rich protein 2 (DLP-2) | Mesenchyme smooth muscle differentiation factor; LIM protein expressed e9.5-e16.5 in smooth muscle | P97315 |
| HCC-1 | DNA-binding factor, inhibits cell growth | Q9D1J3 |
| Moesin Membrane-organizing extension spike protein | Component of “merlin” complex; regulation of NF-κB-induced transcription, actin-modifying protein | P26041 |