Table 5.
Hazard Ratios (Age-, BMI-, and Site-Adjusted) for pQCT Bone Parameters by Quartile for Nonvertebral Fractures in Older Men
| Quartile 1 | Quartile 2 | Quartile 3 | Quartile 4 | |
|---|---|---|---|---|
| FN aBMD | 5.1 (1.9, 13.8) | 1.7 (0.5, 5.1) | 0.6 (0.1, 2.5) | Referent |
| Tibia 4% | ||||
| Total BMC (mg/mm) | 4.1 (1.6, 10.2) | 1.2 (0.4, 3.7) | 0.5 (0.1, 2.0) | Referent |
| Trabecular BMC (mg/mm) | 3.8 (1.4, 10.3) | 1.7 (0.5, 5.2) | 1.6 (0.5, 4.9) | |
| SSIx (mm3) | 7.8 (2.3, 26.6) | 2.9 (0.8, 11.0) | 2.1 (0.5, 8.4) | |
| SSIp (mm3) | 7.6 (2.3, 25.8) | 3.2 (0.9, 11.7) | 1.7 (0.4, 7.2) | |
| Radius 33% | ||||
| Total BMC (mg/mm) | 5.4 (2.0, 14.4) | 0.4 (0.1, 2.1) | 0.8 (0.2, 3.0) | Referent |
| Total CSA (mm2) | 4.1 (1.5, 11.0) | 1.5 (0.5, 4.8) | 1.3 (0.4, 4.3) | |
| Cortical BMC (mg/mm) | 5.2 (2.0, 14.1) | 0.4 (0.1, 2.1) | 0.8 (0.2, 3.1) | |
| Cortical CSA (mm2) | 4.3 (1.7, 10.8) | 0.7 (0.2, 2.4) | 0.5 (0.1, 2.1) | |
| Periosteal circumference(mm) | 4.0 (1.5, 10.8) | 1.5 (0.5, 4.6) | 1.2 (0.4, 4.0) | |
| CSMI (mm4) | 5.8 (2.0, 17.3) | 1.8 (0.5, 6.2) | 0.8 (0.2, 3.4) | |
| PMI (mm4) | 8.0 (2.4, 27.1) | 2.1 (0.5, 8.6) | 1.4 (0.3, 6.2) | |
| SM (mm3) | 7.2 (2.1, 24.6) | 2.1 (0.5, 8.5) | 2.0 (0.5, 8.1) | |
| SSIx (mm3) | 11.7 (2.7, 50.9) | 4.2 (0.9, 20.2) | 2.0 (0.4, 11.0) | |
| SSIp (mm3) | 4.1 (1.5, 10.9) | 1.2 (0.4, 4.0) | 0.8 (0.2, 3.0) | |
| Tibia 33% | ||||
| Total CSA (mm2) | 2.2 (0.9, 5.1) | 1.0 (0.4, 2.8) | 0.8 (0.3, 2.2) | Referent |
| Cortical BMC (mg/mm) | 3.7 (1.3, 10.3) | 2.5 (0.9, 7.1) | 0.6 (0.1, 2.6) | |
| Periosteal circumference(mm) | 2.2 (0.9, 5.2) | 1.0 (0.4, 2.8) | 0.8 (0.3, 2.2) | |
| PMI (mm4) | 2.3 (1.0, 5.3) | 1.1 (0.4, 2.8) | 0.6 (0.2, 1.9) | |
| SSIx (mm3) | 4.2 (1.5, 11.2) | 1.0 (0.3, 3.5) | 1.6 (0.5, 5.0) | |
| Tibia 66% | ||||
| SM (mm3) | 7.8 (2.3, 26.2) | 2.3 (0.6, 9.0) | 1.7 (0.4, 7.1) | Referent |
| SSIp (mm3) | 10.6 (2.5, 45.6) | 4.1 (0.9, 19.2) | 3.0 (0.6, 14.8) | |
BMC = bone mineral content; CSA = cross-sectional area; SSIx = sectional stress-strain index; SSIp = polar stress-strain index; CSMI = cross-sectional moment of inertia; PMI = polar moment of inertia; SM = section modulus.
Note: Values are hazard ratios and 95% confidence intervals. Bold = p < .05.