Table 1.
Baseline Characteristics of FIT Participants Randomized to Placebo (n = 3169)
| Variable | High compliancea | Lower compliancea | p Value |
|---|---|---|---|
| Age, % | .49 | ||
| < 65 years | 51.7% | 51.0% | |
| 65–74 years | 29.8% | 28.1% | |
| 75–81 years | 18.5% | 20.8% | |
| Mean (SD) age in years | 68.2 (6.10) | 68.6 (6.2) | .12 |
| Femoral neck, SDs below peak, % | .90 | ||
| >2.5 | 42.7% | 42.5% | |
| 2.0–2.5 | 26.1% | 27.1% | |
| 1.5–2.0 | 31.1% | 30.4% | |
| Mean (SD) BMD in g/cm2 | |||
| Femoral neck | 0.58 (0.06) | 0.58 (0.07) | .26 |
| Posteroanterior spine | 0.83 (0.14) | 0.82 (0.13) | .54 |
| History of fractures ≥ 45 years, % | 41.9% | 43.5% | .49 |
| Vertebral fractures at baseline, % | 9.0% | 9.9% | .53 |
| Body mass index, mean (SD), kg/m2 | 25.2 (4.1) | 25.4 (4.3) | .26 |
| Self-rated health status, % | < .001 | ||
| Very good/excellent | 66.0% | 54.5% | |
| Good | 29.6% | 36.4% | |
| Fair/poor | 4.5% | 9.1% | |
| Baseline height, mean (SD), cm | 1601 (61) | 1599 (62) | .64 |
| Dietary calcium intake, mean (SD), mg/d | 629 (395) | 649 (399) | .77 |
| Smoking, % | .03 | ||
| Current | 10.6% | 13.3% | |
| Former | 34.0% | 37.2% | |
| Never | 55.4% | 49.5% | |
Note: For this table, compliance was assessed at the end of the study. All other compliance analyses were time-varying. Data were analyzed using chi-square tests for nominal groups and t tests for continuous data.
a
High compliance defined as 80% or greater; lower compliance defined as less than 80%.