Table 3.
Cancellous Bone Dynamic Histomorphometric Parameters Following Treatment
| Sham | OVX | OVX + RAL | OVX + ALN | OVX + RAL + ALN | p Value | |
|---|---|---|---|---|---|---|
| MS/BS % | 8.86 ± 0.82 | 19.15 ± 1.52a | 13.11 ± 1.36a b | 5.96 ± 1.16a b c | 4.57 ± 0.33a b c | pKruskal-Wallis < .001 |
| MAR (µm/day) | 1.12 ± 0.04 | 1.03 ± 0.04 | 1.00 ± 0.07 | 0.77 ± 0.04a b c | 0.85 ± 0.09a b | pANOVA < .001 |
| BFR/BS (µm3/µm2/year) | 36.0 ± 3.4 | 71.9 ± 5.9a | 46.3 ± 4.7b | 18.0 ± 0.7a b c | 14.6 ± 1.9a b c | pKruskal-Wallis < .001 |
Data are presented as ± SE mean. MS/BS % = mineralizing surface; MAR = mineral apposition rate; BFR/BS = bone formation rate.
a
Significantly different from sham.
b
Significantly different from OVX.
c
Significantly different from OVX + RAL.