Figure 1.

CD4⁺ and CD8⁺ T cells/μL and proportion of CD4⁺CD127⁺ T cells do not normalize with ART, whereas IL-7 levels do not differ from HCs after 12 months of ART. Data shown include the total number of CD4⁺ (A) and CD8⁺ (B) T cells/μL, serum IL-7 pg/mL (D), and proportion of CD4⁺CD127⁺ (E) and CD8⁺CD127⁺ (F) T cells in the group of HIV⁺ patients (n = 30) who were followed longitudinally from M0 to M24. The association between CD4⁺ T cells/μL and serum IL-7 levels in HIV⁺ at M0 and HCs is shown (C). Circles (black) represent median values and vertical bars indicate interquartile range (IQR). Gray dashed lines indicate HC median values. P values (gray) at the top of the graphs represent unpaired comparisons between HC and HIV⁺ at each time point, and P values (black) above the IQR bars indicate paired comparisons of HIV⁺ patients at each time point during the therapy to the pretherapy level (M0). Significant P values < .01 are reported, *P = .01 > .001, **P = .001 ≥ .0001, and ***P < .0001. HIV⁺ data are shown as black circles and HCs as gray squares.