Figure 4.

Restoration of naive and CM T cells expressing CD127 after ART. The total number of naive (A-D) and CM (E-F) CD4⁺CD127⁺, CD8⁺CD127⁺, CD4⁺CD127⁻, and CD8⁺CD127⁻ T cells/μL is shown in the group of HIV⁺ patients (n = 30) who were followed from M0 to M24. Circles (black) represent median values and bars indicate interquartile range (IQR). Gray dashed lines indicate HC median values. P values (gray) at the top of the graphs represent unpaired comparisons between HC and HIV⁺ at each time point, and P values (black) above the IQR bars indicate paired comparison of HIV⁺ patients at each time point during the therapy to the pretherapy level (M0). Significant P values < .01 are reported, *P = .01 > .001, **P = .001 ≥ .0001, and ***P < .0001. Naive cells were defined as CD45RO⁻CD27⁺; CM as CD45RO⁺CD27⁺.