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. 2011 Jun 17;118(12):3426–3435. doi: 10.1182/blood-2010-11-320812

Figure 4.

Figure 4

Relative SDF-1α protein expression and Bv8 mRNA expression in LLC tumors after treatment with PTX or PTX in combination with either G-CSF or AMD3100. (A) C57Bl/6 mice bearing 500 mm3 LLC tumors (n = 4-5 mice per group) were treated with PTX or PTX in combination with either G-CSF or AMD3100. Tumors were removed 3 days later and sections evaluated for SDF-1α expression (green; scale bar = 500 μm). (B) Quantification of relative SDF-1α expression is provided. (C) In parallel, mRNA was extracted from the same tumors, and Bv8 mRNA levels were measured by qRT-PCR. ***P < .001 from control group, unless indicated otherwise.