Skip to main content
. 2011 Sep 23;6(9):e23985. doi: 10.1371/journal.pone.0023985

Table 2. Patient and disease characteristics related to the collective used in this study and to the two found clinical relevant clusters.

Factor No. of patients (%) collective No. of patients (%) Cluster 1 No. of patients (%) Cluster 2 p-value
Total 87 (100) 33 (100) 54 (100)
Age
mean 63 63 64
range 33–82 33–82 38–80 0.514
Gender
female 8 (9) 2 (6) 6 (11)
male 79 (91) 31 (94) 48 (89) 0.513
pT category
pT1 29 (33) 14 (42) 15 (28)
pT2 19 (22) 7 (21) 12 (22)
pT3 39 (45) 12 (37) 27 (50) 0.337
pN category
negative 44 (51) 26 (79) 18 (33)
positive 43 (49) 7 (21) 36 (67) 3.9*10−5
Metastasis
cM0 79 (91) 33 (100) 46 (85)
cM1 8 (9) 0 (0) 8 (15) 0.020
Grading
G1 1 (1) 1 (3) 0 (0)
G2 41 (47) 16 (49) 25 (46)
G3 45 (52) 16 (48) 29 (54) 0.414

pT category: depth of tumour invasion; pN category: presence of lymph node metastases; cM category: presence of distant metastases at the time of resection (all classification according to UICC). The p-values for cluster comparison using Chi2-test (for age Mann-Whitney U test) are given. Significant differences were found for lymph node and distant metastases status (bold).