Table 2. Patient and disease characteristics related to the collective used in this study and to the two found clinical relevant clusters.
Factor | No. of patients (%) collective | No. of patients (%) Cluster 1 | No. of patients (%) Cluster 2 | p-value |
Total | 87 (100) | 33 (100) | 54 (100) | |
Age | ||||
mean | 63 | 63 | 64 | |
range | 33–82 | 33–82 | 38–80 | 0.514 |
Gender | ||||
female | 8 (9) | 2 (6) | 6 (11) | |
male | 79 (91) | 31 (94) | 48 (89) | 0.513 |
pT category | ||||
pT1 | 29 (33) | 14 (42) | 15 (28) | |
pT2 | 19 (22) | 7 (21) | 12 (22) | |
pT3 | 39 (45) | 12 (37) | 27 (50) | 0.337 |
pN category | ||||
negative | 44 (51) | 26 (79) | 18 (33) | |
positive | 43 (49) | 7 (21) | 36 (67) | 3.9*10−5 |
Metastasis | ||||
cM0 | 79 (91) | 33 (100) | 46 (85) | |
cM1 | 8 (9) | 0 (0) | 8 (15) | 0.020 |
Grading | ||||
G1 | 1 (1) | 1 (3) | 0 (0) | |
G2 | 41 (47) | 16 (49) | 25 (46) | |
G3 | 45 (52) | 16 (48) | 29 (54) | 0.414 |
pT category: depth of tumour invasion; pN category: presence of lymph node metastases; cM category: presence of distant metastases at the time of resection (all classification according to UICC). The p-values for cluster comparison using Chi2-test (for age Mann-Whitney U test) are given. Significant differences were found for lymph node and distant metastases status (bold).