Table 2. Genes differentially expressed in siPax8 cells versus siNon-targeting cells selected by the PASTAA analysis.
| Common | Synonyms | ENTREZ Gene ID | Affinity Score |
| Down-regulated genes | |||
| Rab17 | RAB17, member RAS oncogene family | 503269 | 2.07 |
| Slc26a7 | Solute carrier family 26, member 7 | 297910 | 2.05 |
| Trib1 | Tribbles homolog 1 (Drosophila) | 78969 | 1.98 |
| Wnt4 | Wingless-type MMTV integration site family, member 4 | 84426 | 1.93 |
| Tg | Thyroglobulin | 24826 | 1.92 |
| Kcnj16 | Potassium inwardly-rectifying channel, subfamily J, member 16 | 29719 | 1.88 |
| Kcnj15 | Potassium inwardly-rectifying channel, subfamily J, member 15 | 170847 | 1,84 |
| Igfbp7 | Insulin-like growth factor binding protein 7 | 289560 | 1.79 |
| Nfkb1 | Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 81736 | 1.79 |
| Egr1 | Early growth response 1 | 24330 | 1.78 |
| Cdh16 | Cadherin 16, KSP-cadherin | 307614 | 1.71 |
| Wbp2 | WW domain binding protein 2 | 192645 | 1.61 |
| Foxe1 | Forkhead box E1 (thyroid transcription factor 2) | 192274 | 1.40 |
| Up-regulated genes | |||
| Runx2 | Runt-related transcription factor 2 | 367218 | 2.28 |
| Cited2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 114490 | 1.95 |
| TAZ | transcriptional co-activator with PDZ-binding motif | 295062 | 1.93 |
| Sparc | secreted protein, acidic, cysteine-rich glycoprotein | 24791 | 1.68 |
All the genes are modulated at least 1.3 fold with a p−value<0.05. We show 13 genes down-regulated and 4 genes up-regulated with affinity score to PAX8≥1.40, selected for further analysis. The genes reported in bold are the ones validated by qPCR after 24 h siRNA transfection.