Skip to main content
. 2011 Sep 23;6(9):e25288. doi: 10.1371/journal.pone.0025288

Figure 4. Exogenous LIF enhanced estradiol (E) + medroxy-progesterone acetate (MPA)-induced in vitro decidualization (measured by PRL secretion) in HESC.

Figure 4

A. LIF treatment significantly (*; p<0.05) promoted E+MPA-induced decidualization in HESC compared to E+MPA-treated control on D14 (n = 5). B. Co-incubation of E+MPA plus LIF and LIF antagonist (LA) significantly (*; p<0.05) inhibited HESC decidualization compared to HESC treated with E+MPA plus LIF (n = 3). Treatments: E 10−8 M; MPA 10−7 M.