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. 2011 Sep 23;6(9):e25288. doi: 10.1371/journal.pone.0025288

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Shuya et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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A. Cytokine secretion by first trimester decidual biopsies (n = 3). B. Cytokine secretion by HESC decidualized with estradiol (E) and medroxy-progesterone acetate (MPA) (n = 5). C. LIF treatment (50 ng/ml) significantly (*; compared to 0.5 ng/ml; p<0.05) induced IL6 secretion by decidualized HESC (n = 5). D. LIF treatment (50 ng/ml) had no significant effect (compared to 0.5 ng/ml; p = 0.222) on IL8 secretion by decidualized HESC (n = 5). E. LIF treatment (50 ng/ml) significantly (*; compared to 0.5 ng/ml; p<0.05) induced IL15 secretion by decidualized HESC (n = 5). F. LIF treatment (50 ng/ml) had no significant effect (compared to 0.5 ng/ml; p = 0.222) on MCP1 secretion by decidualized HESC (n = 5).