Skip to main content
. 2011 Sep 23;6(9):e25268. doi: 10.1371/journal.pone.0025268

Figure 1. Selective loss of N-CoR protein in NSCLC cells.

Figure 1

A & B, Level and integrity of full length N-CoR protein in various lung cancer cells was determined through western blotting assay. Level of β-actin was determined as experimental control. DMS-79 is derived from SCLC while rests of the cells are derived from NSCLC. B, Level of full length N-CoR protein in SAEC treated with nicotine for 48 hours in a dose dependent manner was determined. C, Level of N-CoR transcript in cell lines used in Figure 1 A & B was quantified by real time PCR. The identity of cells used in figure 1A & C is presented in Supporting Information S1. D, Level of full length N-CoR protein in ten histologically confirmed human primary NSCLC cells was determined in western blotting assay with N-CoR antibody. The identity of human samples is presented in Supporting Information S1. E and F, Level of intact N-CoR protein in H2170 cells treated with Kaletra (E) or genistein (F) was determined was determined in western blotting assay.