Table 3. The 5 most extreme functional enrichments for each species on a within-lineage basis.
| Species | Biological process | P-valueA |
| Yeast | Translation | 4.26E-90 |
| Regulation of Translation | 4.70E-51 | |
| Posttranscriptional regulation of gene expression | 6.86E-48 | |
| Ribosome assembly | 4.74E-14 | |
| rRNA processing | 2.32E-13 | |
| C. elegans | Nucleosome organization and assembly | 1.55E-17 |
| Protein-DNA complex organization and assembly | 1.11E-16 | |
| Body morphogenesis | 1.77E-13 | |
| Translation | 5.54E-13 | |
| Chromatin organization | 2.07E-8 | |
| A. thaliana | Structural constituent of cell wall | 7.75E-14 |
| Translational elongation | 6.62E-10 | |
| Plant-type cell wall organization | 1.37E-7 | |
| Structural constituent of ribosome | 7.63E-7 | |
| Chloroplast ribulose bisphosphate carboxylase complex | 1.46E-4 | |
| Chicken | Regulation of multicellular organismal process | 1.95E-7 |
| Sex determination | 2.31E-6 | |
| Regulation of transcription, DNA dependent | 4.67E-6 | |
| Regulation of cell differentiation | 5.28E-6 | |
| Regulation of developmental process | 7.68E-6 | |
| Chimpanzee | Keratinization | 2.67E-18 |
| Feeding behavior | 5.93E-7 | |
| Epidermal cell differentiation | 2.56E-5 | |
| Regulation of transcription, DNA-dependent | 6.59E-5 | |
| Pigment accumulation in tissues | 5.47E-4 | |
| Human | Sequence-specific DNA binding activity | 3.68E-11 |
| Hormone activity | 4.24E-8 | |
| Regulation of transcription, DNA-dependent | 8.99E-7 | |
| RNA polymerase II transcription factor activity | 5.41E-6 | |
| Epidermal cell differentiation | 6.99E-5 |
A
Adjusted P-values for the hypergeometric test obtained using the GOrilla tool (Eden et al., 2009), http://cbl-gorilla.cs.technion.ac.il/.