Table 1. Chaperones and co-chaperones regulated by ORF2.

Affymetrix ID	Gene symbol	Description	Fold change
202581_at	Hsp72(HSPA1A)	Heat shock 70 kDa protein 1A	1.7
200800_s_at	Hsp72(HSPA1A)	-	1.9
1554334_a_at	Hsp40(DNAJ4)	DnaJ (Hsp40) homolog, subfamily A, member 4	2.2
117_at	Hsp70B'(HSPA6)	Heat shock 70 kDa protein 6 (Hsp70B')	3.5
213418_at	Hsp70B'(HSPA6)	-	7.6

The expression profiles of host genes significantly regulated (≥1.7 fold; p value≤0.05) at 60 hours post infection of Huh7 cells with Ad-ORF2 versus Ad-GFP using Affymetrix HGU_133 plus 2.0 array analysis. All values are results of three independent experiments and the fold changes were calculated as log 2 of signal log ratio using MAS5 (Microarray suite, Affymetrix).