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Multivariable adjusted splines relating plasma N-terminal proatrial natriuretic peptide (NT-ANP, x-axis) to change in systolic (Panel A) and diastolic (Panel B) BP on follow-up. Δ, change in BP between examination cycle 6 and 7. Solid vertical line corresponds to the sex-pooled median plasma NT-ANP (295 pmol/L). Adjustment for: sex, age, systolic and diastolic BP, baseline BMI and percent weight change on follow-up.
