Table 2.
Presents the F Ratios of the 24-Hr Deprivation Analysis of Variance (First Column) and the Separate and Interactive Effects of Nicotine Yield and Sensation Seeking During the Experimental Cigarette ANCOVA (Columns 2–4)
| Measure | 24-hr deprivation, df (1,18) | Experimental cigarette analysis |
||
| Nicotine yield, df (2,36) | SS, df (1,18) | Nicotine yield × SS, df (2,36) | ||
| MNWS | ||||
| Crave | 82.65*** | 11.86*** | 1.54 | 0.54 |
| Irritated | 24.83*** | 1.80 | 1.38 | 0.14 |
| Anxious | 18.13*** | 0.89 | 0.05 | 0.07 |
| Difficulty concentrating | 20.78*** | 2.50 | 0.72 | 0.23 |
| Restlessness | 14.43** | 2.80 | 0.51 | 3.21* |
| Headache | 7.57* | 2.93 | 0.09 | 0.15 |
| Drowsy | 7.96* | 0.42 | 1.10 | 1.86 |
| VAS | ||||
| Stimulated | 9.50** | 13.16*** | 0.38 | 3.76* |
| Head rush | 5.04* | 15.79*** | 0.03 | 0.31 |
| Relaxed | 21.81*** | 2.71 | 1.88 | 0.17 |
| Pleasant feeling | 16.01** | 5.85** | 2.80 | 0.08 |
| Stressed | 7.36* | 2.78 | 1.12 | 0.88 |
| Anxious | 10.46** | 6.36** | 3.08 | 2.74 |
| Jittery | 6.28* | 0.08 | 0.12 | 1.28 |
| Sedated | 1.78 | 6.17** | 0.03 | 0.02 |
| Light headed | 0.01 | 14.26*** | 0.02 | 0.83 |
| High | 4.05 | 2.68 | 0.03 | 1.27 |
| Drug effect | 3.82 | 2.80 | 0.96 | 0.52 |
| Like drug | 4.11 | 3.42* | 1.34 | 0.76 |
| Thirsty | 0.93 | 0.89 | 1.79 | 0.67 |
| Sick to stomach | 0.00 | 2.20 | 1.24 | 0.27 |
| POMS | ||||
| Elation | 26.20*** | 8.26*** | 0.44 | 3.39* |
| Total positive | 18.55*** | 8.91*** | 0.88 | 1.93 |
| Vigor | 12.77** | 2.35 | 6.13* | 1.10 |
| Friendliness | 20.22*** | 3.60* | 1.52 | 0.01 |
| Anxiety | 13.53** | 5.90*** | 0.85 | 0.29 |
| Anger | 7.62* | 4.99* | 0.76 | 0.37 |
| Confusion | 8.86** | 0.69 | 0.17 | 0.11 |
| Depression | 2.62 | 4.35* | 0.56 | 0.00 |
| ARCI | ||||
| MBG | 25.27*** | 2.46 | 0.86 | 1.33 |
| A | 10.93** | 0.81 | 3.17 | 0.38 |
| BG | 10.96** | 1.35 | 5.76* | 1.11 |
| LSD | 13.98** | 4.62* | 0.53 | 1.72 |
| PCAG | 18.24*** | 0.91 | 5.10* | 3.32* |
| RA | ||||
| Acquisition | ||||
| Correct responses | 1.25 | 1.73 | 0.00 | 0.61 |
| Incorrect responses | 9.36** | 0.98 | 0.05 | 1.86 |
| Errors index of curvature | 4.21 | 0.43 | 0.27 | 0.24 |
| Performance | ||||
| Correct responses | 26.45*** | 3.91* | 0.96 | 0.70 |
| Incorrect responses | 1.23 | 3.30* | 0.19 | 3.64* |
| DSST | ||||
| Correct responses | 0.63 | 2.88 | 2.15 | 1.29 |
| Incorrect responses | 1.13 | 0.13 | 7.36* | 0.57 |
| RIP | ||||
| Characters per minute | 0.60 | 1.21 | 0.13 | 0.28 |
| Errors of commission | 0.15 | 1.29 | 1.96 | 0.49 |
| Errors of omission | 0.11 | 2.34 | 0.51 | 0.35 |
| Cardiovascular | ||||
| Baseline HR | 38.44*** | 43.30*** | 0.15 | 1.66 |
| Baseline systolic BP | 20.18*** | 1.35 | 0.27 | 1.34 |
| Baseline diastolic BP | 18.55*** | 0.74 | 2.61 | 0.56 |
Note. A = Amphetamine; ANCOVA = analysis of covariance; ARCI = Addiction Research Center Inventory; BG = Benzedrine Group; BP = blood pressure; DSST = Digit–Symbol Substitution Task; HR = heart rate; LSD=lysergic acid diethylamide; MBG = Morphine–Benzedrine Group; MNWS = Minnesota Smoking Withdrawal Scale; PCAG = Pentobarbital, Chlorpromazine, Alcohol Group; POMS = Profile of Mood States; RA = repeated acquisition of response sequences; RIP = rapid information processing; SS = Sensation Seeking group; and VAS = Visual Analog Scale.
*p < .05; **p < .01; ***p < .001.