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. 2011 Jul 20;123(2):590–600. doi: 10.1093/toxsci/kfr183

FIG. 2.

FIG. 2.

Transcriptional profiling of “gene dose-response” model to reveal Nrf2-dependent transcriptional targets. (A) Venn diagram of probe sets that had higher expression in wild-type mice than in Nrf2-null mice (WT > Nrf2-null), in Keap1-KD mice than in wild-type mice (Keap1-KD > WT), and in Keap1-HKO mice than in Keap1-KD mice (Keap1-HKO > Keap1-KD). (B) Venn diagram of probe sets that had lower expression in wild-type mice than in Nrf2-null mice (WT < Nrf2-null), in Keap1-KD mice than in wild-type mice (Keap1-KD < WT), and in Keap1-HKO mice than in Keap1-KD mice (Keap1-HKO < Keap1-KD).