Table 1.
Demographic, clinical and pathological features among men with, and without calculable PSADT after biochemical recurrence (n=535)
| Characteristic | Incalculable PSADT 187 (35) | Calculable PSADT 348 (65) | p-value* |
|---|---|---|---|
| Mean age ± SD (years) | 61.9 ± 6.9 | 63.7 ± 6.1 | 0.003† |
|
| |||
| Race (%) | 0.54 | ||
| White | 89 (48) | 184 (53) | |
| Black | 83 (45) | 140 (40) | |
| Other | 14 (8) | 24 (7) | |
|
| |||
| Mean BMI ± SD (kg/m2) | 28.7 ± 4.7 | 27.6 ± 4.4 | 0.02† |
|
| |||
| Clinical stage (%) | 0.10 | ||
| T1 | 78 (45) | 113 (38) | |
| T2/T3 | 94 (55) | 188 (62) | |
|
| |||
| Biopsy Gleason Score (%) | 0.35 | ||
| <7 | 85 (47) | 175 (54) | |
| 3+4 | 43 (24) | 68 (21) | |
| ≥4+3 | 52 (29) | 83 (25) | |
|
| |||
| Median PSA (ng/mL) at surgery (range) | 8.9 (1.2–69) | 10.1 (0.8–114) | 0.32Φ |
|
| |||
| Median year of surgery | 1999 | 1995 | <0.001Φ |
|
| |||
| Pathological Gleason Sum (%) | 0.08 | ||
| <7 | 45 (25) | 113 (33) | |
| 3+4 | 65 (36) | 122 (36) | |
| ≥4+3 | 71 (39) | 106 (31) | |
|
| |||
| Number of positive surgical margins (%) | 0.002 | ||
| 0 | 56 (36) | 142 (52) | |
| 1 | 39 (25) | 71 (26) | |
| 2 | 40 (25) | 41 (15) | |
| 3 | 18 (11) | 15 (6) | |
| 4 | 4 (3) | 5 (2) | |
|
| |||
| Median months to biochemical recurrence (range) | 11 (0.5–111) | 21 (0.5–143) | <0.001Φ |
|
| |||
| Median year of recurrence | 2000 | 1998 | <0.001Φ |
|
| |||
| Pathological Grouping | 0.002 | ||
| Organ confined (T2), margin negative (M−) | 30 (17) | 104 (31) | |
| T2M+ or T3 +/−M+, No SV invasion (SV−) | 102 (57) | 162 (48) | |
| Seminal Vesicle Invasion (SV+) | 47 (26) | 70 (21) | |
|
| |||
| No. Patients at each surgical center (%) | <0.001 | ||
| Center #1 | 57 (30) | 88 (26) | |
| Center #2 | 27 (14) | 59 (17) | |
| Center #3 | 16 (9) | 62 (18) | |
| Center #4 | 17 (9) | 55 (16) | |
| Center #5 | 70 (37) | 84 (24) | |
*
p-value from chi-squared test unless otherwise indicated
†
p-value from t-test
Φ
p-value from rank-sum test