Table 4.

Predictors of mortality according to univariate and multivariate logistic regression analysis

Predictor (independent) variable	Survivors N (%)	Non-survivors n (%)	Univariate analysis		Multivariate analysis
			O.R. (95% C.I.)	p-value	(O.R. 95% C.I.)	p-value
Age
< 40	51(98.1)	1 (1.9)
≥40	24(75.0)	8 (25.0)	2.33(1.25-3.42)	0.032	4.61(2.72-7.91)	0.002
Sex
Male	42 (87.5)	6 (12.5)
Female	33 (91.7)	3 (8.3)	1.25 (0.32-3.56)	0.896	2.93 (0.94-3.81)	0.983
Premorbid illness
Yes	2 (33.3)	4 (66.7)
No	73 (93.6	5 (6.4)	6.21(1.49-7.01)	0.039	3.78(2.98-7.90)	0.017
Previous PUD
Yes	23 (88.0)	3(12.0)
No	52 (89.7)	6 (10.3)	1.75(0.76-4.34)	0.896	3.11(0.98-4.88)	0.345
HIV status
Positive	1(12.5)	7 (87.5)
Negative	74(97.4)	2 (2.6)	0.56(0.12-0.86)	0.005	1.74(1.21-4.98)	0.001
CD 4+ count
< 200 cells/μl	1(50.0)	1 (50.0)
≥ 200 cells/μl	4(66.7)	2 (33.3)	5.91(2.76-7.99)	0.001	1.65(1,22-7.43)	0.000
Duration of illness
<24 hours	23 (92.0)	2 (8.0)
≥24 hours	48 (87.3)	7 (12.7)	2.32(0.54-6.45)	0.986	0.09(0.02-1.11)	0.315
Shock on admission (SBP < 90 mmHg)
Yes	28 (77.8)	8 (22.2)
No	47 (87.9)	1(2.1)	7.9(3.98-9.88)	0.022	3,74(2,11-7.76)	0.005
Timing of surgical treatment
<48 hours	19 (95.0)	1 (5.0)
≥ 48 hours	56 (87.5)	8 (12.5%)	2.87(2.11-7.21)	0.044	2.91(1.22-6.66)	0.028
Amount of fluid (mls
< 200	19 (95.0)	1 (5.0)
≥200	56(87.5)	8 (12.5)	0.67(0.23-4.65)	0.982	1.61(0.89-2.73)	0.067
Site of perforation
Duodenum	72 (93.4)	5 (6.6)
Gastric	2 (33.3)	4 (66.7)	5.81(3.33-6.92)	0.012	1.35(1.11-3.86)	0.018
Size of ulcer
Sealed	7 (100.0)	0(0)
<5 mm	12 (92.3)	1(7.7)
≥5 mm	56 (87.5)	8(12.5)	1.98(0.45-3.82)	0.987	3.13(0.99-4.89)	0.453
Complications
Present	18 (72.0)	7(28.0)
Absent	57(96.6)	2 (3.4)	1.98(1.54-7.93)	0.005	2.86(2.22-6.45)	0.011