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. Author manuscript; available in PMC: 2012 Dec 1.
Published in final edited form as: Behav Brain Res. 2011 Aug 11;225(2):473–481. doi: 10.1016/j.bbr.2011.08.005

Figure 7.

Figure 7

Six vs. eight-week old age of onset of nicotine self-administration effect on later cocaine self-administration to estrus phase, infusions (mean±sem) per 45-min. session in female rats. The rats that had begun nicotine access at six weeks self-administered significantly (p<0.05) more nicotine during the second week of access compared with rats that began nicotine access at eight weeks of age. No significant differences were seen with the subsequent switch to cocaine self-administration.