Fig. 5.

Inhibition of tubulin assembly by noscapine analogs in vitro. Effects of various analogs on tubulin polymerization were assessed by monitoring the increase in light scattering at 350 nm as described under ‘Materials and Methods’. Each data point was obtained by subtracting the absorbance values of corresponding noscapine analogs in the absence of tubulin. Data are representative of three independent experiments performed in triplicate (p< 0.05).