Table 1.
Metabolic data at 1, 2, and 8 weeks after inducing diabetes.
1 week | 2 week | 8 week | ||
---|---|---|---|---|
Body weight (g) | ||||
Control | 204 ± 6.3 | 241 ± 10.4 | 380 ± 13.3 | |
Diabetic | 198 ± 4.7 | 225 ± 11.5 | 248 ± 16.6* | |
Kidney weight (mg/g BW) | ||||
Control | 5.8 ± 0.4 | 5.6 ± 0.8 | 4.5 ± 0.7 | |
Diabetic | 5.9 ± 0.6 | 6.1 ± 1.0 | 6.7 ± 0.9* | |
UAE (μg/day) | ||||
Control | 110 ± 7.3 | 121 ± 8.1 | 137 ± 14.7 | |
Diabetic | 116 ± 5.7 | 125 ± 9.4 | 458 ± 24.5* | |
HbA1c (%) | ||||
Control | 3.7 ± 0.4 | 3.8 ± 0.6 | 3.8 ± 0.5 | |
Diabetic | 3.8 ± 0.3 | 4.3 ± 0.7 | 7.8 ± 0.9* |
Data are means ± SEM; *P < 0.05 versus the control group. BW: body weight; UAE: urinary albumin excretion; HbA1c: hemoglobin A1c.