Table 1.
Characteristics of the study population, with or without metabolic syndrome (MS).
| Characteristics | MS-free (n = 205) | MS (n = 88) | P |
|---|---|---|---|
| Age (years) | 60.9 ± 9.3 | 60.8 ± 9.6 | NS* |
| Male sex (%) | 59.5 | 42.0 | 0.006† |
| Coronary Artery Disease (%) | 61.0 | 79.5 | 0.002† |
| BMI (kg/m²) | 25.5 ± 2.9 | 28.7 ± 5.1 | <0.001* |
| Hypertension (%) | 57.1 | 89.8 | <0.001† |
| Smoking (%) | 52.8 | 54.9 | NS † |
| Diabetes (%) | 7.8 | 46.5 | <0.001† |
| Glucose (mmol/L) | 5.40 ± 0.98 | 7.01 ± 2.29 | <0.001* |
| Creatinine (µmol/L) | 90.1 ± 64.2 | 89.4 ± 21.9 | NS* |
| Total cholesterol (mmol/L) | 5.16 ± 1.13 | 5.29 ± 1.19 | NS* |
| LDL-cholesterol (mmol/L) | 3.18 ± 0.95 | 3.33 ± 1.11 | NS* |
| HDL-cholesterol (mmol/L) | 1.35 ± 0.34 | 1.07 ± 0.31 | <0.001* |
| Triglycerides (mmol/L) | 1.47 ± 0.65 | 2.33 ± 0.98 | <0.001* |
| Apo A-I (g/L) | 1.30 ± 0.26 | 1.13 ± 0.23 | <0.001* |
| Apo B (g/L) | 0.98 ± 0.24 | 1.08 ± 0.28 | 0.003* |
| TBBLase activity (U/mL) | 3.45 ± 0.98 | 3.02 ± 1.02 | 0.001* |
| DEPCyMCase activity (mU/mL) | 23.83 ± 5.65 | 20.60 ± 6.05 | <0.001* |
| Paraoxonase activity (U/L) | 120.8 ± 79.1 | 102.6 ± 71.5 | 0.030* |
| Arylesterase activity (kU/L) | 101.3 ± 31.4 | 86.8 ± 32.5 | <0.001* |
| Normalized lactonase activity | 145.0 ± 24.3 | 146.1 ± 35.0 | NS* |
|
| |||
| PON1 Gln192Arg ‡ | |||
| Gln/Gln | 50.3 | 45.6 | |
| Gln/Arg | 40.0 | 49.4 | NS† |
| Arg/Arg | 9.7 | 5.1 | * |
|
| |||
| PON1 Leu55Met‡ | |||
| Leu/Leu | 38.0 | 38.0 | |
| Leu/Met | 48.9 | 44.3 | NS† |
| Met/Met | 13.1 | 17.7 | |
*by t-test; †by χ² test; ‡PON1 genotype data were available for 264/293 (90.1%) subjects, that is, 185 MS-free and 79 with MS; NS: no significant.