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. Author manuscript; available in PMC: 2012 Sep 23.

Published in final edited form as: Vaccine. 2011 Jul 21;29(42):7267–7275. doi: 10.1016/j.vaccine.2011.07.021

Table 3.

Virus Neutralizing Antibody Titers in Mice Immunized with Various Doses of Recombinant DEN-80E Proteins Formulated with ISCOMATRIX™ Adjuvant

DEN-80E Antigen Dose	Geometric Mean PRNT₅₀ Titer

	DENV1	DENV2	DENV3	DENV4
30 µg	NT^*	NT	1741	728
10 µg	1450	10,556	1550	526
3 µg	1053	8574	1908	278
1 µg	504	4595	1414	144
0.3 µg	35	2096	400	28
0.1 µg	<20	590	NT	NT
PBS	<10	<10	<10	<10

NT - Not tested