Figure 2. Vibration-evoked allodynia is not mediated by myelinated tactile afferents.

Mean vibration-evoked responses (±SEM; n = 10; grey) were expressed as a percentage of the baseline muscle pain (unshaded). Cutaneous vibration evoked a significant increase in HS-induced muscle pain (allodynia) during compression of myelinated afferents. Allodynia was abolished upon anaesthesia of the residual cutaneous input (C afferents). In the adjacent, non-anaesthetized skin (C afferents intact) within the innervation territory of blocked myelinated afferents, allodynia was preserved. ***P < 0.001.