Figure 3. Vibration-evoked allodynia is mediated by C-tactile afferents in hairy skin.

Mean vibration-evoked responses (±SEM; n = 7; grey) were expressed as a percentage of the baseline muscle pain (unshaded). Cutaneous vibration evoked a significant increase in HS-induced muscle pain (allodynia). Allodynia was abolished upon anaesthesia of C afferents in the skin (unmyelinated cutaneous block). In the adjacent, non-anaesthetized skin with a full complement of sensory fibres, allodynia was preserved. *P < 0.05; **P < 0.01; ***P < 0.001.