Table 1.
Properties of strong cation exchangers
| Trade name | Base matrix | Mean particle size (µm) | Ion capacity (µequ/mL) | Lysozyme dynamic binding capacity at 10% breakthrough (mg/mL settled resin) | Polyclonal hIgG dynamic binding capacity at 10% breakthrough (mg/mL settled resin) |
| Eshmuno™ S | cross-linked hydrophilic vinylether with “tentacle” polymer functional groups | 85 | 50–100 | 1001 | 802 |
| Fractogel* EMD SO3− (M) | Methacrylate with “tentacle” polymer functional groups | 65 | 70–110 | 903 | 602 |
| Toyopearl* GigaCap S-650 M | Methacrylate with proprietary polymer functional groups | 75 | 100–00 | 1674 | 1002 |
1
residence time 1 min; pH 7.0.
2
residence time 2 min; pH 5.0.
3
residence time 2 min; pH 7.0.
4
residence time 0.85 min; pH 4.7.28