Figure 5.

Comparative analysis of the activation of Natural Killer cells by CHO- and EB66-produced antibodies. Efficiency of activation of NK cells purified from two independent healthy human donors was assessed in parallel for the monoclonal antibody targeting the undisclosed target “X” and produced either on CHO or on EB66 cells. Induction of expression of INFγ (A and B) and of the membrane antigen CD107a (C and D) was determined by flow cytometry with NK cells cultured without Interleukin 2 (IL-2) or with 5 or 100 units of IL-2.