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. 2011 Jul 1;2(4):440–448. doi: 10.4161/mabs.2.4.12203

Figure 2.

Figure 2

Lintuzumab (SGN-33) does not enhance the direct cytotoxic effect of 5-azacytidine against AML cell lines in vitro. HL60cy and KG-1 AML cell lines were incubated with increasing concentrations of 5-azacytidine, lintuzumab or 5-azacytidine in combination with 10 µg/ml lintuzumab or cross-linked lintuzumab (XL-SGN-33) as described in Materials and Methods. Similar results were obtained with HEL9217 cells (data not shown). Data shown are mean ± SEM of duplicate values graphed as % untreated (untreated = 100%).