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Changes in mitochondrial activity in MCF7 cells and fibroblasts in co-culture. FACS tracings for mitochondrial activity (MitoTracker red fluorescence) in fibroblasts or cancer cells, either cultured alone or in combination, are shown. Interestingly, during co-culture, MCF7 cells show a shift to the right, as indicated by the blue arrow. Conversely, during co-culture, stromal fibroblasts show just the opposite effect, with a shift to the left.
