Comparison between survival of BrdU-labeled cells at 24 h and 4 weeks after LPS injection in WT and COX-1-/- mice. The surviving BrdU-cells in LPS-injected COX-1-/- mice was severely reduced by 49% after 4 weeks, whereas the number of BrdU-cells was not significantly affected in LPS-injected WT mice. Data are means ± SEM (n = 5, 24 h after LPS; n = 4, 4 weeks after LPS); **p < 0.01, LPS-injected COX-1-/- vs. LPS-injected WT mice, 4 weeks after injection.