Table 2.
Reference allele frequencies and measures of association for g.15,190T>C (rs2270676 encoding F66F) and g.15,240G>A (rs17215437 encoding R83H), based on data from 474 and 1,140 Caucasian controls, respectively.
| Healthy controls (Nunrelated) | study | g.15,190T>C (F66F) frequency in controls |
g.15,190T>C (F66F) controls vs. tinnitus patients |
g.15,240G>A (R83H) frequency in controls |
g.15,240G>A (R83H) controls vs. tinnitus patients |
|---|---|---|---|---|---|
| "White" Brazilian (40) | [23] | - | - | 0.000 | n.s. |
| French (506) | [24] | - | - | 0.008 | n.s. |
| German (321) | [25] | - | - | 0.005 | n.s. |
| U.S., European descent (180) | [22] | 0.117 | n.s.* | 0.003 | n.s. |
| Caucasian (48) | PharmGKB PS203664 | 0.083 | n.s. | 0.010 | n.s. |
| Caucasian (45) | dbSNP ss65626119 | 0.089 | n.s. | - | - |
| Caucasian (45) | dbSNP ss65626296 | - | - | 0.011 | n.s. |
| Utah residents with Northern and Western European ancestry from the CEPH collection (113) | HapMap-CEU ss38798969 | 0.093 | n.s. | - | - |
| Tuscans in Italy (88) | HapMap-TSI ss38798969 | 0.108 | n.s. | - | - |
dbSNP data refer to NCBI build 132, HapMap data refer to two out of the 11 populations in phase 3.
*n.s. = not significant