Figure 1.

Single-nucleotide polymorphisms (SNPs) in the region of the heme oxygenase 1 (HMOX1) gene whose allele frequency was > 10% in European-American Coriell samples. Shading represents the strength of pair-wise linkage disequilibrium (LD) with a black-to-white gradient reflecting higher to lower r² values. Bin: a group of SNPs where the alleles are highly associated. *: tag SNPs; †: SNPs which were excluded from the study.