Table 1. Relationship between AP-2α expression and clinicopathologic features of patients with gastric cancer.
Variables | Number | AP-2α expression | P value | |
Low | High | |||
Age(years) | 0.192 | |||
≤60 | 270 | 117 | 153 | |
>60 | 211 | 79 | 132 | |
Gender | 0.446 | |||
Male | 326 | 129 | 197 | |
Female | 155 | 67 | 88 | |
Tumor size (cm) | 0.449 | |||
≤5.0 | 309 | 122 | 187 | |
>5.0 | 172 | 74 | 98 | |
Histological grade | 0.001* | |||
Well differentiated (G1) | 18 | 3 | 15 | |
Moderately differentiated (G2) | 166 | 45 | 121 | |
Poorly differentiated (G3) | 297 | 148 | 149 | |
Location | 0.002* | |||
Proximal | 271 | 106 | 165 | |
Distant | 186 | 72 | 114 | |
Total | 24 | 18 | 6 | |
Radical resection | 0.004* | |||
Yes | 410 | 156 | 254 | |
No | 71 | 40 | 31 | |
Tumor invasion (T) | 0.018* | |||
T1 | 35 | 12 | 23 | |
T2 | 43 | 13 | 30 | |
T3 | 98 | 33 | 65 | |
T4a | 256 | 109 | 147 | |
T4b | 49 | 29 | 20 | |
Nodal status (N) | 0.006* | |||
N0 | 135 | 44 | 91 | |
N1 | 94 | 36 | 58 | |
N2 | 107 | 40 | 67 | |
N3 | 145 | 76 | 69 | |
Metastasis status (M) | 0.008* | |||
M0 | 425 | 164 | 261 | |
M1 | 56 | 32 | 24 | |
TNM Staging | <0.001* | |||
Stage I | 50 | 14 | 36 | |
Stage II | 118 | 35 | 83 | |
Stage III | 256 | 114 | 142 | |
Stage IV | 57 | 33 | 24 |
*Statistically significant (P<0.05).