Table 1.
Characteristics of Children that Completed the Study
| Characteristic | No. (%) or Median (IQR) |
|---|---|
| No. of patients | 12 (100) |
| Age (years) | 10.5 (8.9 - 12.4) |
| FVC (% predicted) | 107 (101.5 - 116.0) |
| FEV1 (% predicted) | 108 (102.5 - 117.5) |
| Height (percentile) | 36.5 (16.0 - 70.5) |
| Weight (percentile) | 39.5 (27.5 - 71.5) |
| BMI (percentile) | 48.5 (35.0 - 69.5) |
| Genotype: | |
| F508del homozygous | 9 (75%) |
| F508del heterozygous | 2 (17%) |
| Other | 1 (8%) |
| Routine Medications: | |
| Albuterol | 3 (25%) |
| rhDNase (dornase alpha) | 11 (92%) |
| Salmeterol/fluticasone | 7 (58%) |
| Azithromycin | 5 (42%) |
| Inhaled tobramycin | 2 (17%) |
| Organisms cultured at screening: | |
| Staphylococcus aureus | 5 (42%) |
| Aspergillus fumigates | 3 (25%) |
| Normal/Mixed Respiratory Flora | 2 (17%) |
| Pseudomonas aeruginosa | 2 (17%) |
| Haemophilus influenza | 2 (17%) |
| MRSA | 1 (8%) |
| Stenotrophomonas multiphilia | 1 (8%) |
| Paecilomyces variotll | 1 (8%) |
Abbreviation: IQR, interquartile range