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. 2011 Sep 26;6(9):e25194. doi: 10.1371/journal.pone.0025194

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This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

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DCX mRNA expression [normalised to the geometric mean of four housekeeping genes, shown as a % of control mean for control and schizophrenia groups (bar = mean)] was not altered in the brains of people with schizophrenia (n = 37) compared to control subjects (n = 37, p = 0.5, co-varying for age, pH, PMI, and RIN) (A). (B) DCX mRNA expression did not correlate with the density of superficial IWMNs in controls, and was negatively correlated with superficial IWMNs in patients with schizophrenia (C). (D) In development there was a positive correlation between DCX mRNA expression (normalised to the geometric mean of four housekeeping genes, shown as a % of the mean expression of the neonate group) and superficial IWMN density.