Table 1.
Plasticity of the mossy fiber tract.
| Group | Volume of mossy fiber subfields (mm3 × 10−2) | ||||
|---|---|---|---|---|---|
| Hilus | SMF | IMF | Total MF projection | ||
| Enriched environment | 1.026 ± 0.1 | 1.414 ± 0.067 | 0.527 ± 0.0419 | 2.884 ± 0.178 | |
| Control | 0.985 ± 0.054 | 1.330 ± 0.069 | 0.437 ± 0.0203 | 2.837 ± 0.120 | |
| TIMEPOINT AFTER STATUS EPILEPTICUS | |||||
| 9 days | Control | 1.092 ± 0.05 | 1.232 ± 0.14 | 0.397 ± 0.02 | 2.721 ± 0.165 |
| Seizure | 1.116 ± 0.15 | 1.142 ± 0.10 | 0.372 ± 0.03 | 2.630 ± 0.199 | |
| 15 days | Control | 0.99 ± 0.08 | 1.491 ± 0.15 | 0.374 ± 0.02 | 2.856 ± 0.132 |
| Seizure | 1.226 ± 0.10 | 1.723 ± 0.06 | 0.544 ± 0.03** | 3.493 ± 0.172* | |
| 28 days | Control | 0.958 ± 0.08 | 1.331 ± 0.12 | 0.358 ± 0.02 | 2.647 ± 0.173 |
| Seizure | 0.922 ± 0.05 | 1.621 ± 0.13 | 0.460 ± 0.02* | 3.004 ± 0.153 | |
The sizes of the mossy fiber subfields are dynamically regulated with neurogenic stimuli. SP-MF, suprapyramidal mossy fibers; IMF, infrapyramidal mossy fibers; MF, mossy fibers. *p < 0.05, **p < 0.001.