Table 3.
Screening performance of the two esophagogastroduodenoscopies in subjects with or without chronic atrophic gastritis (mean ± SD) n (%)
| Total subjects | CAG |
||
| Positive | Negative | ||
| Screened by transnasal EGD | |||
| Screened subjects | 1382 | 560 | 822 |
| Age (yr) | 53.4 ± 15.4 | 60.3 ± 11.8c | 47.0 ± 14.5 |
| Males | 684 (49.4)a | 316 (56.4)a | 368 (44.8)a |
| Smokers | 267 (19.3) | 121 (21.6) | 146 (17.8) |
| Subjects with gastric neoplasia/DR | 23/0.0166 | 22/0.0286c | 1/0.00122a |
| Location of neoplasia (U/M/L) | 8/7/8 | 8/6/8 | 0/1/0 |
| Adenoma cases/DR | 3/0.0022 | 3/0.00536 | 0/0 |
| Size of adenoma (mm) | 9.7 ± 4.0 | 9.7 ± 4.0 | 0 |
| Cancer cases/DR | 20/0.0145 | 19/0.0315c | 1/0.00122 |
| Size of cancer (mm) | 32.6 ± 19.5a | 34.1 ± 18.8a | 5 ± 0 |
| Morphological cancer type (I-IIa/IIb/IIc-III/Ad) | 6/1/5/8 | 6/1/4/8 | 0/0/1/0 |
| With intestinal-type cancer | 18 (90.0) | 18 (94.7) | 0 (0) |
| Depth of invasion (m/sm/pm-) | 5/7/8 | 4/7/8 | 1/0/0 |
| With early cancer | 12 (60.0) | 11 (57.9)a | 1 (100) |
| Screened by transoral EGD | |||
| Screened subjects | 1942 | 800 | 1142 |
| Age (yr) | 53.5 ± 15.6 | 62.3 ± 11.4c | 47.3 ± 14.2 |
| Males | 758 (39.0) | 363 (45.3) | 395 (34.6) |
| Smokers | 411 (21.2) | 165 (20.6) | 246 (21.6) |
| Subjects with gastric neoplasia/DR | 32/0.0164 | 24/0.0300c | 8/0.0070 |
| Location of neoplasia (U/M/L) | 12/8/12 | 8/7/9 | 4/1/3 |
| Adenoma cases/DR | 9/0.0046 | 7/0.00875c | 2/0.00175 |
| Size of adenoma (mm) | 10.8 ± 7.9 | 11.7 ± 8.8 | 7.5 ± 3.5 |
| Cancer cases/DR | 23/0.0118 | 17/0.0213c | 6/0.00525 |
| Size of cancer (mm) | 22.3 ± 12.8 | 19.4 ± 11.7 | 31.4 ± 12.1 |
| Morphological cancer type (I-IIa/IIb/IIc-III/Ad) | 6/0/12/5 | 6/0/9/2 | 0/0/3/3 |
| With intestinal-type cancer | 15 (65.2) | 12 (70.6)c | 2 (33.3) |
| Depth of invasion (m/sm/pm-) | 15/3/5 | 13/2/2 | 2/1/3 |
| With early cancer | 8 (78.3) | 15 (88.2) | 3 (50.0) |
a
P < 0.05 vs transoral;
c
P < 0.05 vs CAG-negative. CAG: Chronic atrophic gastritis; DR: Detection rate; U: Upper third of the stomach; M: Middle third of the stomach; L: Lower third of the stomach; EGD: Esophagogastroduodenoscopy.