Table 2.
Number of paediatric middle ear fluid isolates (MEF), and among them, number of PCV-7 and 19A isolates, with per-group percentages of non-susceptibility to penicillin (PEN), amoxicillin (AMX), cefotaxime (CTX), and erythromycin (ERY)
| 97-00 | 2001 | 2002 | 2003 | 2004 | 2005 | 2006 | 2007 | 2008 | 2009 | |
|---|---|---|---|---|---|---|---|---|---|---|
| MEF (n) | 481 | 210 | 171 | 159 | 180 | 166 | 176 | 173 | 220 | 141 |
| PEN | 69.0 | 58.1 | 58.5 | 42.8 | 36.7 | 45.8 | 41.5 | 47.4 | 53.2 | 51.1 |
| AMX | - | 8.1 | 8.8 | 8.2 | 6.7 | 6.0 | 10.8 | 19.0 | 25.0 | 24.1 |
| CTX | 5.2 | 4.8 | 4.1 | 1.9 | 6.1 | 1.8 | 1.1 | 6.9 | 6.8 | 8.5 |
| ERY | 55.3 | 51.0 | 51.5 | 45.3 | 42.8 | 48.8 | 49.4 | 48.6 | 52.7 | 44.7 |
| PCV-7 (n) | 340 | 132 | 109 | 77 | 64 | 40 | 33 | 23 | 22 | 15 |
| PEN | 88.5 | 82.6 | 83.5 | 67.5 | 68.7 | 77.5 | 69.7 | 73.9 | 81.8 | 86.7 |
| AMX | - | 12.1 | 13.8 | 13.0 | 17.2 | 15.0 | 21.2 | 26.1 | 50.0 | 53.3 |
| CTX | 6.5 | 7.6 | 6.4 | 3.9 | 12.5 | 2.5 | 3.0 | 8.7 | 9.1 | 6.7 |
| ERY | 65.0 | 57.6 | 63.3 | 58.4 | 64.1 | 67.5 | 63.6 | 43.5 | 36.4 | 53.2 |
| 19A (n) | 32 | 20 | 21 | 27 | 38 | 53 | 55 | 67 | 103 | 50 |
| PEN | 50.0 | 40.0 | 23.8 | 44.4 | 47.4 | 62.3 | 67.3 | 70.1 | 80.6 | 84.0 |
| AMX | - | 0.0 | 0.0 | 7.4 | 2.6 | 5.7 | 21.8 | 38.8 | 37.9 | 38.0 |
| CTX | 3.1 | 0.0 | 0.0 | 0.0 | 7.9 | 3.8 | 1.8 | 14.9 | 11.7 | 20.0 |
| ERY | 50.0 | 65.0 | 33.3 | 59.3 | 68.4 | 79.2 | 78.2 | 82.1 | 85.4 | 76.0 |
Non-susceptibility: PEN ≥ 0.12 μg/ml; AMX ≥ 4 μg/ml; CTX ≥ 2 μg/ml; ERY ≥ 0.5 μg/ml