Table 1.
Demographic data of the multidrug-resistant tuberculosis patients with or without pyrazinamide (PZA) resistancea
| PZA susceptibility test | P value | ||
|---|---|---|---|
| Resistant, n = 36 | Susceptible, n = 30 | ||
| Age (MD) | 58.3 (21.0) | 57.8 (17.8) | 0.91 |
| Gender | |||
| Male | 25 (69.4%) | 24 (80%) | 0.33 |
| Female | 11 (30.6%) | 6 (20%) | |
| Previous anti-TB treatment | |||
| Yes | 11 (30.6%) | 10 (33.3%) | 0.81 |
| No | 25 (69.4%) | 20 (66.7%) | |
| Sputum smear | |||
| Positive | 17 (47.2%) | 22 (73.3%) | 0.032 |
| Negative | 19 (52.8%) | 8 (26.7%) | |
| Disease site | |||
| Pulmonary TB | 35 (97.2%) | 28 (93.3%) | 0.45 |
| Extrapulmonary TB | 1 (2.8%) | 2 (6.7%) | |
| Presence of cavity in radiogram | |||
| Yes | 8 (22.2%) | 12 (40%) | 0.12 |
| No | 28 (77.8%) | 18 (60%) | |
| Ethambutol resistance | |||
| Yes | 21 (58.3%) | 10 (33.3%) | 0.043 |
| No | 15 (41.7%) | 20 (66.7%) | |
| Streptomycin resistance | |||
| Yes | 24 (66.7%) | 11 (36.7%) | 0.015 |
| No | 12 (33.3%) | 19 (63.3%) | |
| Genotyping | |||
| Beijing strain | 21 (58.3%) | 16 (53.3%) | 0.68 |
| Non-Beijing strain | 15 (41.7%) | 14 (46.7%) | |
aData are presented as n(%) unless otherwise stated.