Table 4.
Mean of Log2 Active Thymulin Titer, CD4+ and CD8+ Cell Count, and CD4+/CD8+ Ratio and Viral Load by Substance Use
| Drug | N | Log2 thymulin titer [mean (SD)] | CD4+cell count [mean (SD)] | CD8+cell count [mean (SD)] | CD4+/CD8+[mean (SD)] | Viral load (copies/ml) [mean (SD)] |
|---|---|---|---|---|---|---|
| Alcohol | ||||||
| No | 48 | 2.54 (1.88) | 204.20 (29.79) | 415.71 (60.64) | 0.49 (0.32) | 8.8E4 (1.9E5) |
| Yes | 32 | 2.12 (1.56) | 273.70 (48.38) | 569.44 (102.27) | 0.50 (0.37) | 7.3E4 (1.6E5) |
| Marijuana | ||||||
| No | 54 | 2.43 (1.79) | 359.67 (259.53) | 844.63 (511.15) | 0.48 (0.33) | 8.6E4 (1.9E5) |
| Yes | 26 | 2.27 (1.73) | 318.08 (168.76) | 761.42 (419.91) | 0.53 (0.36) | 7.5E4 (1.8E5) |
| Cocaine | ||||||
| No | 40 | 2.77 (1.94)a | 364.88 (212.96) | 899.50 (520.63) | 0.47 (0.30) | 7.1E4 (1.8E5) |
| Yes | 40 | 1.97 (1.48) | 327.57 (252.87) | 738.42 (433.20) | 0.53 (0.38) | 9.4E4 (1.9E5) |
| Alcohol and marijuana | ||||||
| No | 67 | 2.45 (1.78) | 357.53 (243.59) | 832.34 (504.72) | 0.51 (0.34) | 8.3E4 (1.9E5) |
| Yes | 13 | 2.00 (1.68) | 287.38 (166.97) | 739.69 (348.42) | 0.45 (0.33) | 8.2E4 (1.5E5) |
| Alcohol and cocaine | ||||||
| No | 58 | 2.57 (1.85) | 347.70 (203.21) | 828.25 (490.87) | 0.49 (0.31) | 7.9E4 (1.8E5) |
| Yes | 22 | 1.86 (1.39) | 341.54 (303.28) | 788.00 (466.77) | 0.52 (0.40) | 9.1E4 (1.9E5) |
| Marijuana and cocaine | ||||||
| No | 64 | 2.44 (1.82) | 356.14 (248.68) | 858.66 (509.15) | 0.48 (0.33) | 8.6E4 (1.9E5) |
| Yes | 16 | 2.12 (1.50) | 306.00 (158.85) | 655.06 (317.62) | 0.56 (0.38) | 6.9E4 (1.43E5) |
a
Significantly different at p < 0.05 (Mann–Whitney U test).