Fig. 1.

Identification of genes differentially expressed in junctional zone tissue from Holtzman Sprague-Dawley (HSD), Dahl salt-sensitive (DSS), and Brown Norway (BN) rat strains. A: gene profiling of junctional zone tissue from HSD and BN rat strains using the Affymetrix Rat 230 2.0 chip. Among the transcripts expressed in junctional zone, 182 transcripts were highly expressed in HSD and 171 transcripts were highly expressed in BN (fold change >2, P < 0.05). B: Gene Ontology (GO) analysis of the DNA microarray results. C–N: selected genes exhibiting strain differences in their expression patterns based on DNA microarray analysis were verified by quantitative (q) RT-PCR for HSD, DSS, and BN rat strains. *Significant differences (P < 0.05).