Table 2.
Additive genetic correlations between obesity- and diabetes-related traits of children enrolled in Viva La Familia
| Weight | BMI | Waist | FFM | FM | % FM | |
|---|---|---|---|---|---|---|
| Glucose | 0.02 (0.14) | 0.10 (0.13) | 0.09 (0.13) | −0.03 (0.14) | −0.03 (0.14) | 0.02 (0.12) |
| Insulin | 0.54 (0.11) | 0.62 (0.09) | 0.68 (0.08) | 0.31 (0.14) | 0.58 (0.10) | 0.59 (0.10) |
| C-peptide | 0.28 (0.11) | 0.36 (0.10) | 0.32 (0.10) | 0.11 (0.12) | 0.32 (0.10) | 0.34 (0.10) |
| HOMA-IR | 0.50 (0.11) | 0.60 (0.10) | 0.64 (0.09) | 0.28 (0.15) | 0.54 (0.11) | 0.55 (0.10) |
| HDL | −0.17 (0.12) | −0.10 (0.11) | −0.15 (0.11) | −0.28 (0.11) | −0.14 (0.11) | −0.13 (0.10) |
| Total T3 | −0.12 (0.14) | −0.04 (0.14) | 0.01 (0.14) | −0.37 (0.15) | −0.02 (0.14) | 0.03 (0.12) |
| Free T3 | −0.12 (0.13) | −0.16 (0.13) | −0.10 (0.12) | −0.10 (0.13) | −0.03 (0.13) | 0.04 (0.12) |
| CRP | 0.35 (0.13) | 0.44 (0.12) | 0.45 (0.11) | 0.33 (0.14) | 0.40 (0.12) | 0.44 (0.11) |
| sICAM-1 | −0.22 (0.12) | −0.16 (0.11) | −0.14 (0.11) | −0.13 (0.11) | −0.17 (0.11) | −0.06 (0.10) |
| Leptin | 0.67 (0.08) | 0.70 (0.07) | 0.68 (0.07) | 0.30 (0.14) | 0.78 (0.05) | 0.78 (0.05) |
| Ghrelin | −0.43 (0.11) | −0.50 (0.10) | −0.49 (0.10) | −0.34 (0.11) | −0.48 (0.10) | −0.46 (0.09) |
Additive genetic correlation (ρG) ± SE adjusted for age, sex, age2, age × sex, and age2 × sex. Statistically significant ρG values >0.20. FFM, fat-free mass; FM, fat mass.