Table 4.
SNP | rs12857529 | rs74123739 | 9966359_49 | 10510452_139 | 9967402_248 | 9967400_279 | 9967404_111 | 9966359_424 | 9967406_194 | 9967406_274 |
---|---|---|---|---|---|---|---|---|---|---|
Minor allele | A | C | A | G | A | A | T | C | A | A |
frequency | 0.009 | 0.007 | 0.007 | 0.002 | 0.001 | 0.001 | 0.002 | 0.001 | 0.001 | 0.001 |
Type | promoter | 3′-UTR | promoter | promoter | coding synon | missense mutation | missense mutation | promoter | nonsense mutation | missense mutation |
Glucose | 0.973 | 0.295 | 0.382 | 0.383 | 0.753 | 0.300 | 0.859 | 0.657 | 0.736 | 0.737 |
Insulin | 0.507 | 0.081 | 0.057 | 0.020 | 0.685 | 0.333 | 0.129 | 0.727 | 0.687 | 0.453 |
Weight | 0.006 | 0.037 | 0.006 | 0.001 | 0.102 | 0.129 | 0.351 | 0.033 | 0.104 | 0.362 |
BMI | 0.014 | 0.029 | 0.004 | 0.001 | 0.105 | 0.103 | 0.084 | 0.031 | 0.108 | 0.437 |
Waist | 0.018 | 0.025 | 0.004 | 0.0004 | 0.109 | 0.076 | 0.098 | 0.102 | 0.114 | 0.484 |
FFM | 0.007 | 0.115 | 0.121 | 0.001 | 1.000 | 0.027 | 0.805 | 0.046 | 1.000 | 0.211 |
FM | 0.024 | 0.008 | 0.008 | 0.001 | 0.073 | 0.063 | 0.245 | 0.006 | 0.077 | 0.610 |
HDL | 0.621 | 0.792 | 0.847 | 0.061 | 0.00002 | 0.563 | 0.599 | 0.705 | 0.00002 | 0.200 |
Total T3 | 0.197 | 0.184 | 0.167 | 0.680 | 0.007 | 0.005 | 0.482 | 0.480 | 0.007 | 0.822 |
Free T3 | 0.199 | 0.518 | 0.420 | 0.240 | 0.006 | 0.002 | 0.117 | 0.153 | 0.006 | 0.672 |
CRP | 0.038 | 0.783 | 0.626 | 0.033 | 0.028 | 0.770 | 0.009 | 0.606 | 0.029 | 0.778 |
sICAM-1 | 0.946 | 0.498 | 0.408 | 0.817 | 0.021 | 0.631 | 0.006 | 0.889 | 0.026 | 0.001 |
Leptin | 0.343 | 0.049 | 0.024 | 0.050 | 0.360 | 0.068 | 0.031 | 0.010 | 0.354 | 0.881 |
Ghrelin | 0.412 | 0.675 | 0.762 | 0.006 | 0.150 | 0.015 | 0.021 | 0.030 | 0.153 | 0.200 |
All measured genotype analysis models included age, sex, age × sex, age2, and age2 × sex as covariates (n = 934). Nominal P values are shown uncorrected for multiple testing. P values ≤0.01 are highlighted in boldface.