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. 2011 Jul 19;43(18):1029–1037. doi: 10.1152/physiolgenomics.00019.2011

Table 5.

Percent of the population variance contributed by the nominally significant SNPs (%)

SNP rs12857529 rs74123739 9966359_49 10510452_139 9967402_248 9967400_279 9967404_111 9966359_424 9967406_194 9967406_274
Minor allele A C A G A A T C A A
frequency 0.009 0.007 0.007 0.002 0.001 0.001 0.002 0.001 0.001 0.001
Type promoter 3′-UTR promoter promoter coding synon missense mutation missense mutation promoter nonsense mutation missense mutation
Glucose 0 0.03 0 0.26 0.03 0.20 0.03 0.02 0.03 0
Insulin 0.002 0.43 0.50 1.40 0.04 0 0.30 0.03 0.04 0.11
Weight 0.40 0.01 1.10 2.90 0.18 0.08 0.08 0.32 0.15 0.12
BMI 0.20 0.80 1.20 2.80 0.12 0.16 0.30 0.70 0.10 0.11
Waist 0.20 0.80 1.20 3.10 0.16 0.19 0.30 0.40 0.14 0.09
FFM 0.55 0.53 0.50 3.60 0 0.40 0 0.70 0 0.30
FM 0.23 1.11 1.10 3.10 0.20 0.20 0.08 1.10 0.20 0.05
HDL 0 0.03 0.02 1.00 0.70 0 0.04 0.05 0.77 0.09
Total T3 0.30 0.21 0.22 0.02 0.50 0.90 0.09 0 0.40 0
Free T3 0.20 0.02 0.05 0.40 0.77 0.80 0.40 0.30 0.70 0.02
CRP 0.24 0.01 0.03 1.10 0.43 0 0.08 0.03 0.40 0.02
sICAM-1 0.01 0.10 0.13 0.02 0.50 0.30 0.90 0 0.50 0.90
Leptin 0.04 0.64 0.80 1.00 0.04 0.16 0.40 0.80 0.03 0.01
Ghrelin 0 0.01 0 2.20 0.20 0.50 0.80 1.10 0.20 0.16