Table 2. Amino Acid Mean and t-Test for Cases vs Control.
| Case (n=189) | Control (n=104) | |||||
|---|---|---|---|---|---|---|
| Amino Acid | Mean μM |
SD | Mean μM |
SD | p T-test 2-sided | padjusted |
| Taurine | 159.4 | 52.4 | 174.3 | 58.2 | 0.0319 | .691 |
|
|
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| Aspartate1 | 32.4 | 14.3 | 35.9 | 16.8 | 0.1419 | .717 |
|
|
||||||
| Threonine | 134.7 | 40.1 | 153.6 | 40.4 | 0.0001 | .015 |
|
|
||||||
| Serine | 132.1 | 33.3 | 142.9 | 41.0 | 0.0322 | .691 |
|
|
||||||
| Asparagine | 68.3 | 19.5 | 78.1 | 25.8 | 0.0012 | .205 |
|
|
||||||
| Glutamate | 98.9 | 56.9 | 129.7 | 102.4 | 0.0373 | .743 |
|
|
||||||
| Glutamine | 854.7 | 182.1 | 867.0 | 213.3 | 0.7509 | .190 |
|
|
||||||
| Glycine | 287.9 | 80.5 | 321.1 | 110.9 | 0.0074 | .244 |
|
|
||||||
| Alanine | 451.6 | 122.4 | 527.5 | 163.3 | <0.0001 | .003 |
|
|
||||||
| Citrulline | 34.7 | 12.2 | 38.4 | 9.7 | 0.0040 | .066 |
|
|
||||||
| α-amino butyric acid | 21.3 | 9.3 | 21.0 | 10.7 | 0.5714 | .018 |
|
|
||||||
| Valine | 254.1 | 58.8 | 268.0 | 66.6 | 0.1003 | .219 |
|
|
||||||
| Total Homocysteine | 14.5 | 6.6 | 15.4 | 9.4 | 0.9271 | .060 |
|
|
||||||
| Methionine | 23.7 | 6.5 | 25.7 | 8.0 | 0.0287 | .742 |
|
|
||||||
| Isoleucine | 67.8 | 19.8 | 69.3 | 22.8 | 0.7742 | .005 |
|
|
||||||
| Leucine | 156.5 | 39.0 | 161.6 | 47.0 | 0.4789 | .001 |
|
|
||||||
| Tyrosine | 66.9 | 18.2 | 74.5 | 19.8 | 0.0008 | .105 |
|
|
||||||
| Phenylalanine | 79.0 | 19.5 | 86.5 | 44.8 | 0.1314 | .126 |
|
|
||||||
| Ornithine | 97.8 | 32.4 | 126.3 | 55.2 | <0.0001 | .00001 |
|
|
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| Lysine | 206.1 | 50.7 | 217.4 | 53.7 | 0.0698 | .092 |
|
|
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| 1-methyl-histidine | 19.1 | 13.8 | 18.3 | 10.5 | 0.8477 | .374 |
|
|
||||||
| Histidine | 77.4 | 19.7 | 90.0 | 22.2 | <0.0001 | .00002 |
|
|
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| 3-methyl-histidine2 | 22.9 | 6.1 | 24.0 | 5.8 | 0.0845 | .675 |
|
|
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| Arginine | 98.7 | 31.1 | 84.0 | 33.8 | <0.0001 | .00001 |
|
|
||||||
| Total Cysteine | 401.8 | 98.2 | 374.5 | 87.6 | 0.0172 | <.000001 |
|
|
||||||
| Proline | 214.3 | 83.2 | 230.9 | 63.8 | 0.0373 | .373 |
|
| ||||||
| Factor 1 | 0.131 | 0.934 | -0.237 | 1.074 | 0.0025 | NA |
|
|
||||||
| Factor 2 | -0.070 | 0.864 | 0.128 | 1.203 | 0.1049 | NA |
|
|
||||||
| Factor 3 | 0.032 | 1.019 | -0.058 | 0.967 | 0.461 | NA |
1
Aspartate co-elutes with reduced glutathione.
2
Tryptophan co-elutes with 3-methylhistidine.