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Distribution of doxorubicin in the multidrug-resistant K562 tumor cells. It was observed under confocal microscopy after incubating multidrug-resistant K562 tumor cells with free doxorubicin for (A) 0.5 hours, (B) 2 hours, (C) 8 hours, and doxorubicin-loaded copolymer polyethylene glycol-polycaprolactone micelles for (D) 30 minutes, (E) 2 hours, and (F) 8 hours.
