Table 1.

Impact of overexpression of Grx1 on content of NF-κB dependent pro-inflammatory cytokines in C10 cells stimulated with LPS. C10 cells were transfected with 1 μg of Flag-Grx1 plasmid, or PcDNA3 control, and 24 h later stimulated with 10 μg/ml of LPS for 24, 48 or 72 h. Cytokine content in medium was assessed via ELISA assays, * p< 0.05, ANOVA, compared to PcDNA group at the same time.

	PcDNA3	Flag GRX1
hr	RANTES
-	207 ± 28	286 ± 46
24	906 ± 97	1282 ± 114
48	1210 ± 206	2079 ± 482*
72	1375 ± 242	1787 ± 289
	IL-6
-	16.1 ± 1.4	20.4 ± 3.9
24	19.5 ± 3.4	33.5 ± 3*
48	19.0 ± 4.1	33.5 ± 3*
72	16.5 ± 2.4	26.6 ± 4*
	GM-CSF
-	2.2 ± 0.1	2.3 ± 0.4
24	4.0 ± 1.0	3.4 ± 1.1
48	6.2 ± 0.9	10.9 ± 1.7*
72	2.9 ± 0.9	9.9 ± 2.3*
	KC
-	386 ± 12	369.7 ± 98
24	927 ± 121	941.0 ±67
48	3179 ± 297	3261.2 ± 265
72	3471 ± 492	4644.4 ± 401*